Lenalidomide HCl

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Chemical Structure| 1243329-97-6 同义名 : CC-5013 hydrochloride; Lenalidomide hydrochloride
CAS号 : 1243329-97-6
货号 : A451300
分子式 : C13H14ClN3O3
纯度 : 98+%
分子量 : 295.72
MDL号 : N/A
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.38mL

0.68mL

0.34mL

16.91mL

3.38mL

1.69mL

33.82mL

6.76mL

3.38mL
参考文献

[1]Omran A, Ashhab MU, et al. Effects of MRP8, LPS, and lenalidomide on the expressions of TNF-α , brain-enriched, and inflammation-related microRNAs in the primary astrocyte culture. ScientificWorldJournal. 2013 Sep 21;2013:208309.

[2]Kotla V, Goel S, et al. Mechanism of action of lenalidomide in hematological malignancies. J Hematol Oncol. 2009 Aug 12;2:36.