Fagomine

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Chemical Structure| 53185-12-9 同义名 : D-Fagomine
CAS号 : 53185-12-9
货号 : A448695
分子式 : C6H13NO3
纯度 : 98+%
分子量 : 147.17
MDL号 : MFCD18782654
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 35 mg/mL(237.82 mM)
生物活性
描述 D-Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench), present in the human diet and now available as a pure crystalline product.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.79mL

1.36mL

0.68mL

33.97mL

6.79mL

3.40mL

67.95mL

13.59mL

6.79mL
参考文献

[1]Mena-Barragan T, Garcia-Moreno MI, et al. Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts. Eur J Med Chem. 2016 Oct 4;121:880-891.

[2]Ramos-Romero S, Molinar-Toribio E, et al. Effect of (D)-fagomine on excreted Enterobacteria and weight gain in rats fed a high-fat high-sucrose diet. Obesity (Silver Spring). 2014 Apr;22(4):976-9.