3,4-Dihydro-2,2-Dimethyl-2H-Naphtho[1,2-B]pyran

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Chemical Structure| 16274-33-2 同义名 : -
CAS号 : 16274-33-2
货号 : A445975
分子式 : C15H16O
纯度 : 98+%
分子量 : 212.29
MDL号 : -
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran is a natural product isolated and purified from the herbs of Catalpa ovata.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.71mL

0.94mL

0.47mL

23.55mL

4.71mL

2.36mL

47.11mL

9.42mL

4.71mL
参考文献

[1]Savage RE, Tyler AN, et al. Identification of a novel glucosylsulfate conjugate as a metabolite of 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b] pyran-5,6-dione (ARQ 501, beta-lapachone) in mammals. Drug Metab Dispos. 2008 Apr;36(4):753-8.

[2]Boothman DA, Greer S, Pardee AB. Potentiation of halogenated pyrimidine radiosensitizers in human carcinoma cells by beta-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b] pyran- 5,6-dione), a novel DNA repair inhibitor. Cancer Res. 1987 Oct 15;47(20):5361-6.