Maxacalcitol

产品说明书

Print
Chemical Structure| 103909-75-7 同义名 : 22-Oxacalcitriol; Maxacalcitrol; 22-Oxa-1,25-dihydroxyvitamin D3.; alpha,25-Dihydroxy-22-oxavitamin D3; Sch 209579; Prezios; OCT; MC 1275; Maxacalcitriol
CAS号 : 103909-75-7
货号 : A435260
分子式 : C26H42O4
纯度 : 98+%
分子量 : 418.61
MDL号 : MFCD00871502
存储条件:

Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(119.44 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

生物活性
描述 Maxacalcitol is non-calcemic vitamin D3 analog and ligand of VDR-like receptors.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.39mL

0.48mL

0.24mL

11.94mL

2.39mL

1.19mL

23.89mL

4.78mL

2.39mL

参考文献

[1]Inoue K, Matsui I, et al. Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3. Lab Invest. 2012 Dec;92(12):1686-97.

[2]Karashima T, Hashikawa K, et al. Successful treatment of Bowen's disease with topical maxacalcitol. Acta Derm Venereol. 2012 Nov;92(6):660-1.