MS049 2HCl

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Chemical Structure| 2095432-59-8 同义名 : MS049 (hydrochloride); MS049; MS049 dihydrochloride
CAS号 : 2095432-59-8
货号 : A431561
分子式 : C15H26Cl2N2O
纯度 : 98+%
分子量 : 321.29
MDL号 : N/A
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 MS049 dihydrochloride is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.11mL

0.62mL

0.31mL

15.56mL

3.11mL

1.56mL

31.12mL

6.22mL

3.11mL
参考文献

[1]Shen Y, Szewczyk MM, et al. Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6. J Med Chem. 2016 Oct 13;59(19):9124-9139.