ST 2825

产品说明书

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Chemical Structure| 894787-30-5 同义名 : -
CAS号 : 894787-30-5
货号 : A423062
分子式 : C27H28Cl2N4O5S
纯度 : 98%
分子量 : 591.51
MDL号 : MFCD30207830
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(177.51 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 ST 2825 is a MyD88 pharmacologic inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.69mL

0.34mL

0.17mL

8.45mL

1.69mL

0.85mL

16.91mL

3.38mL

1.69mL
参考文献

[1]Fantò N, Gallo G, et al. Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88. J Med Chem. 2008 Mar 13;51(5):1189-202.

[2]Loiarro M, Capolunghi F, et al. Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound. J Leukoc Biol. 2007 Oct;82(4):801-10.