Camicinal

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Chemical Structure| 923565-21-3 同义名 : Gsk962040
CAS号 : 923565-21-3
货号 : A404042
分子式 : C25H33FN4O
纯度 : 98+%
分子量 : 424.55
MDL号 : N/A
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(247.32 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 GSK962040 is a small molecule, selective motilin receptor agonist with pEC50 of 7.9.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.36mL

0.47mL

0.24mL

11.78mL

2.36mL

1.18mL

23.55mL

4.71mL

2.36mL
参考文献

[1]Leming S, Broad J, et al. GSK962040: a small molecule motilin receptor agonist which increases gastrointestinal motility in conscious dogs. Neurogastroenterol Motil. 2011 Oct;23(10):958-e410.

[2]Sanger GJ, Westaway SM, et al. GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility. Neurogastroenterol Motil. 2009 Jun;21(6):657-64, e30-1.