MRT67307 2HCl

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Chemical Structure| 1781882-89-0 同义名 : MRT67307 Dihydrochloride; MRT67307 HCl
CAS号 : 1781882-89-0
货号 : A402551
分子式 : C26H38Cl2N6O2
纯度 : 98%
分子量 : 537.52
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 MRT67307 Hydrochloride is a potent and dual IKKε and TBK1 inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.86mL

0.37mL

0.19mL

9.30mL

1.86mL

0.93mL

18.60mL

3.72mL

1.86mL
参考文献

[1]Clark K, MacKenzie KF, et al. Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16986-91.

[2]Clark K, Peggie M, et al. Novel cross-talk within the IKK family controls innate immunity. Biochem J. 2011 Feb 15;434(1):93-104.