5,7-Dihydroxychromone
产品说明书
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同义名 : | 5,7-二羟基色原酮 ;DHC |
| CAS号 : | 31721-94-5 | |
| 货号 : | A390989 | |
| 分子式 : | C9H6O4 | |
| 纯度 : | 97% | |
| 分子量 : | 178.14 | |
| MDL号 : | MFCD14583153 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(589.42 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | 5,7-Dihydroxychromone, a natural product isolated and purified from the bark of Garcinia cambogia., exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal, and induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
5.61mL 1.12mL 0.56mL |
28.07mL 5.61mL 2.81mL |
56.14mL 11.23mL 5.61mL |
| 参考文献 |
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