Alovudine
产品说明书
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同义名 : | 阿洛夫定（3'-脱氧-3'-氟胸苷） ;3'-Fluoro-3'-deoxythymidine; 3′-Deoxy-3′-fluorothymidine; NSC 140025; MIV-310; FddThd; CL 184824; FLT |
| CAS号 : | 25526-93-6 | |
| 货号 : | A374199 | |
| 分子式 : | C10H13FN2O4 | |
| 纯度 : | 98% | |
| 分子量 : | 244.22 | |
| MDL号 : | MFCD00056058 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(429.94 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 25 mg/mL(102.37 mM) |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Alovudine (3'-Fluoro-3'-deoxythymidine) serves as a marker of DNA synthesis and is less affected by inflammatory changes than 18F-Fluorodeoxyglucose (FDG), making it a more suitable biomarker for pancreatic cancer. Additionally, alovudine exhibits activity against orthopoxviruses[1].[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.09mL 0.82mL 0.41mL |
20.47mL 4.09mL 2.05mL |
40.95mL 8.19mL 4.09mL |
| 参考文献 |
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