Furosemide sodium

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Chemical Structure| 41733-55-5 同义名 : Furosemide钠盐 ;Lasix; Frusemide Sodium; Sodium furosemide
CAS号 : 41733-55-5
货号 : A360297
分子式 : C12H10ClN2NaO5S
纯度 : 95%
分子量 : 352.73
MDL号 : MFCD23379919
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 145 mg/mL(411.08 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(283.5 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Furosemide sodium is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.84mL

0.57mL

0.28mL

14.18mL

2.84mL

1.42mL

28.35mL

5.67mL

2.84mL
参考文献

[1]Rais-Bahrami K, Majd M, et al. Use of furosemide and hearing loss in neonatal intensive care survivors. Am J Perinatol. 2004 Aug;21(6):329-32.

[2]Tia S, Wang JF, Kotchabhakdi N, et al. Developmental changes of inhibitory synaptic currents in cerebellar granule neurons: role of GABA(A) receptor alpha 6 subunit. J Neurosci. 1996 Jun 1;16(11):3630-40.