| 生物活性 | |||
|---|---|---|---|
| 描述 | Rebaudioside A is a steviol glycoside. As a α - glucosidase inhibitor, IC50[2]. In vivo, Rebaudioside A (10-9 M) reduced the ATP-sensitive potassium channel (K(ATP)) conductance in a glucose-dependent manner. Moreover, rebaudioside A stimulated the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner[3]. In vitro,Reb A was non-genotoxic in a bone marrow micronucleus test in mice at doses up 750 mg/kg bw and in an unscheduled DNA synthesis test in rats at 2000 mg/kg bw[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.03mL 0.21mL 0.10mL |
5.17mL 1.03mL 0.52mL |
10.34mL 2.07mL 1.03mL |
| 参考文献 |
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