Lupenone

产品说明书

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Chemical Structure| 1617-70-5 同义名 : NSC 281807; lupeone; Lup-20(29)-en-3-one
CAS号 : 1617-70-5
货号 : A340952
分子式 : C30H48O
纯度 : 98%
分子量 : 424.7
MDL号 : MFCD00083578
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

无水乙醇: 8 mg/mL(18.84 mM)，配合低频超声，并水浴加热至45℃助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇
生物活性
描述 Lupenone, a natural product isolated and purified from the roots of Pueraria thomsonii Benth., effectively inhibits adipocyte differentiation through downregulation of related transcription factor, particularly the PPARγ gene.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.24mL

11.77mL

2.35mL

1.18mL

23.55mL

4.71mL

2.35mL
参考文献

[1]Ahn EK, Oh JS. Lupenone isolated from Adenophora triphylla var. japonica extract inhibits adipogenic differentiation through the downregulation of PPARγ in 3T3-L1 cells. Phytother Res. 2013 May;27(5):761-6.

[2]Villareal MO, Han J, et al. Lupenone from Erica multiflora leaf extract stimulates melanogenesis in B16 murine melanoma cells through the inhibition of ERK1/2 activation. Planta Med. 2013 Mar;79(3-4):236-43.