Boc-NH-PEG3-CH2COOH

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Chemical Structure| 462100-06-7 同义名 : -
CAS号 : 462100-06-7
货号 : A334552
分子式 : C13H25NO7
纯度 : 97%
分子量 : 307.34
MDL号 : MFCD22376773
存储条件:

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(341.64 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Boc-NH-PEG3-CH2COOH is a polyethylene glycol (PEG)-based linker designed for the construction of PROTACs, indicating its role in bridging two distinct ligands within these molecules for targeted protein degradation[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.25mL

0.65mL

0.33mL

16.27mL

3.25mL

1.63mL

32.54mL

6.51mL

3.25mL

参考文献

[1]Vollmer S, et al. Design, Synthesis, and Biological Evaluation of MEK PROTACs. J Med Chem. 2020 Jan 9;63(1):157-162.