Sardomozide

产品说明书

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Chemical Structure| 149400-88-4 同义名 : CGP 48664; SAM-486A
CAS号 : 149400-88-4
货号 : A332744
分子式 : C11H14N6
纯度 : 95%
分子量 : 230.27
MDL号 : MFCD00920906
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Sardomozide is a second-generation polyamine synthesis inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.34mL

0.87mL

0.43mL

21.71mL

4.34mL

2.17mL

43.43mL

8.69mL

4.34mL
参考文献

[1]Millward MJ, Joshua A, et al. Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma. Invest New Drugs. 2005 Jun;23(3):253-6.

[2]Dorhout B, te Velde RJ, et al. In vivo effects of 4-amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) and alpha-difluoromethylornithine (DFMO) on L1210 growth, cell-cycle phase distribution and polyamine contents. Int J Cancer. 1995 Sep 15;62(6):738-42.