Rhoifolin

产品说明书

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Chemical Structure| 17306-46-6 同义名 : Apigenin 7-O-Neohesperidoside; Rhoifoloside; NSC649413; Apigenin-7-O-rhamnoglucoside
CAS号 : 17306-46-6
货号 : A330186
分子式 : C27H30O14
纯度 : 99%+
分子量 : 578.52
MDL号 : MFCD00016773
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 60 mg/mL(103.71 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Rhoifolin, a natural product isolated and purified from the leaves of Turpinia arguya Seem, hows monolithic proliferation inhibitory activities against Hela, A549 and MCF-7 cell lines, and may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.73mL

0.35mL

0.17mL

8.64mL

1.73mL

0.86mL

17.29mL

3.46mL

1.73mL
参考文献

[1]Rao YK, Lee MJ, et al. Insulin-Mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells. Evid Based Complement Alternat Med. 2011;2011:624375.

[2]Ishii K, Urano S, et al. Determination of rhoifolin and daidzin in human plasma by high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1994 May 13;655(2):300-4.