L-Ornithine

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Chemical Structure| 70-26-8 同义名 : 鸟氨酸 ;(S)-2,5-Diaminopentanoic acid
CAS号 : 70-26-8
货号 : A329366
分子式 : C5H12N2O2
纯度 : 98%
分子量 : 132.16
MDL号 : MFCD00242584
存储条件:

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 50 mg/mL(378.33 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 L-ornithine has an antifatigue effect in increasing the efficiency of energy consumption and promoting the excretion of ammonia.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00033371 Colorectal Cancer ... 展开 >> Familial Adenomatous Polyposis 收起 << Phase 2 Terminated(Slow recruitment.) - United States, Texas ... 展开 >> M D Anderson Cancer Center Houston, Texas, United States, 77030 收起 <<
NCT00033371 - Terminated(Slow recruitment.) - -
NCT00021294 Non-melanomatous Skin Cancer ... 展开 >> Precancerous/Nonmalignant Condition 收起 << Phase 2 Completed - United States, Arizona ... 展开 >> Arizona Cancer Center Tucson, Arizona, United States, 85724 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

7.57mL

1.51mL

0.76mL

37.83mL

7.57mL

3.78mL

75.67mL

15.13mL

7.57mL

参考文献

[1]Sidhu SS, Sharma BC, et al. L-ornithine L-aspartate in bouts of overt hepatic encephalopathy. Hepatology. 2017 Jul 27.

[2]Ytrebo LM, Kristiansen RG, et al. L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure. Hepatology. 2009 Jul;50(1):165-74.