HEPES

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Chemical Structure| 7365-45-9 同义名 : -
CAS号 : 7365-45-9
货号 : A318293
分子式 : C8H18N2O4S
纯度 : 97%
分子量 : 238.3
MDL号 : MFCD00006158
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 250 mg/mL(1049.08 mM)，配合低频超声助溶
生物活性
描述 HEPES, recognized as a nonvolatile zwitterionic chemical buffering agent, is widely utilized in cell culture due to its effective buffering range of pH 6.8 to 8.2. It also acts as a significant inducer of lysosome biogenesis[1][2][3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.20mL

0.84mL

0.42mL

20.98mL

4.20mL

2.10mL

41.96mL

8.39mL

4.20mL
参考文献

[1]Suzuki T, et al. Nonvolatile buffer coating of titanium to prevent its biological aging and for drug delivery. Biomaterials. 2010;31(18):4818-4828.

[2]Sledź P, et al. An experimental charge density of HEPES. Acta Crystallogr B. 2010;66(Pt 4):482-492.

[3]Tol MJ, et al. HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution. Autophagy. 2018;14(3):437-449.