CTPB

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Chemical Structure| 586976-24-1 同义名 : -
CAS号 : 586976-24-1
货号 : A314356
分子式 : C31H43ClF3NO2
纯度 : 99%
分子量 : 554.13
MDL号 : MFCD08702707
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 60 mg/mL(108.28 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 CTPB effectively activates the p300 histone acetyltransferase (HAT) enzyme[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.80mL

0.36mL

0.18mL

9.02mL

1.80mL

0.90mL

18.05mL

3.61mL

1.80mL
参考文献

[1]Sivanandam M, et al. Investigation of activation mechanism and conformational stability of N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxybenzamide and N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamidein the active site of p300 histone acetyl transferase enzyme by molecular dynamics and binding free-energy studies. J Biomol Struct Dyn. 2018 Oct 9:1-38.