Anamorelin HCl

产品说明书

Print
Chemical Structure| 861998-00-7 同义名 : RC-1291 hydrochloride; ONO-7643 hydrochloride; Anamorelin hydrochloride
CAS号 : 861998-00-7
货号 : A308314
分子式 : C31H43ClN6O3
纯度 : 98+%
分子量 : 583.16
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 165 mg/mL(282.94 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 50 mg/mL(85.74 mM)，配合低频超声，并水浴加热至45℃助溶
动物实验配方：
生物活性
描述 Anamorelin hydrochloride is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.71mL

0.34mL

0.17mL

8.57mL

1.71mL

0.86mL

17.15mL

3.43mL

1.71mL
参考文献

[1]Zhang H, Garcia JM. Anamorelin hydrochloride for the treatment of cancer-anorexia-cachexia in NSCLC. Expert Opin Pharmacother. 2015 Jun;16(8):1245-53.

[2]Currow DC, Abernethy AP. Anamorelin hydrochloride in the treatment of cancer anorexia-cachexia syndrome. Future Oncol. 2014 Apr;10(5):789-802.