Ro 67-4853

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Chemical Structure| 302841-89-0 同义名 : -
CAS号 : 302841-89-0
货号 : A304725
分子式 : C19H19NO4
纯度 : 98+%
分子量 : 325.36
MDL号 : MFCD20270618
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Ro 67-4853 is a drug used in scientific research, which acts as a selective positive allosteric modulator for the metabotropic glutamate receptor subtype mGluR1.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.07mL

0.61mL

0.31mL

15.37mL

3.07mL

1.54mL

30.74mL

6.15mL

3.07mL
参考文献

[1]Hemstapat K, de Paulis T, et al. A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators. Mol Pharmacol. 2006 Aug;70(2):616-26.

[2]Kammermeier PJ. Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins. BMC Neurosci. 2006 Jan 4;7:1.