Human IL-13RA2 (C-Fc, HEK293)
产品说明书
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同义名 : | 重组人IL-13RA2蛋白(C-Fc, HEK293) ;Recombinant Human IL-13RA2 (C-Fc, HEK293); IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R |
| CAS号 : | N/A | |
| 货号 : | A2926539 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 64 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -70°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
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| 描述 | Interleukin-13 Receptor alpha 2 (IL-13 R alpha 2), also known as IL-13 binding protein, and CD213a2. IL-13RA2 is a transmembrane receptor which binds IL-13 with very high affinity. Due to its very short cytoplasmic region lacking signaling motifs, IL-13RA2 is generally thought to act primarily as a “decoy” receptor, sequestering IL-13 and thus preventing excessive IL-13 signaling via the complex IL-13RA1 and IL-4RA.In rodents, IL-13RA2 is released as a soluble factor and its expression correlates with a decreased responsiveness to IL-13 in chronic granulomatous inflammation in the liver, airway inflammation and airwayhyperreactivity, and immune and functional response to nematode infection. | ||