Mouse DLL3 (C-6His, HEK293)
产品说明书
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同义名 : | 重组小鼠DLL3蛋白(C-6His, HEK293) ;Recombinant Mouse DLL3 (C-6His, HEK293); Delta-like protein 3; Drosophila Delta homolog 3; Delta3; DLL3 |
| CAS号 : | N/A | |
| 货号 : | A2926455 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 48.7 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -70°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 is highly expressed in tumor cells and could be involved in the modification of tumor (immune) microenvironment. Neuroendocrine carcinomas are very aggressive tumors with few treatment options. DLL3 seems to be an optimal target for therapeutic intervention, as it is expressed mainly on the membrane of tumor cells with neuroendocrine origin. | ||