Human GCGR N-ECD (C-6His, HEK293)
产品说明书
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同义名 : | 重组人GCGR N-ECD蛋白(C-6His, HEK293) ;Recombinant Human GCGR N-ECD (C-6His, HEK293); Glucagon receptor; GCGR; GL-R |
| CAS号 : | N/A | |
| 货号 : | A2926381 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 13.9 kDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | The glucagon receptor (GCGR), a class B G protein-coupled receptor (GPCR), is the principal regulator of glucagon action in the liver. Glucagon receptor (Gcgr) plays a key role in regulating both glucose and lipid metabolisms. Glucagon is a linear peptide containing 29 amino acids. It is secreted by islet α cells and mainly targets the liver cells. After glucagon specifically binds to GCGR, it promotes liver glycogen breakdown and increases blood glucose levels to stimulate insulin release. | ||