2019-nCoV NSP8 (C-6His, E.coli)

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Chemical Structure| N/A 同义名 : 重组2019-nCoV NSP8蛋白(C-6His, E.coli) ;Recombinant 2019-nCoV NSP8 (C-6His, E.coli); SARS-CoV 2 nsp8
CAS号 : N/A
货号 : A2926241
分子式 : -
纯度 : 85% determined by reducing SDS-PAGE.
分子量 : 25 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -70°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.