Human ASS1 (N-6His, E.coli)

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Chemical Structure| N/A 同义名 : 重组人ASS1蛋白(N-6His, E.coli) ;Recombinant Human ASS1 (N-6His, E.coli); Argininosuccinate Synthase; Citrulline--Aspartate Ligase; ASS1; ASS
CAS号 : N/A
货号 : A2925997
分子式 : -
纯度 : 95% determined by reducing SDS-PAGE.
分子量 : 42.8 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -70°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.