Mouse MMP-9 (C-10His, HEK293)

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Chemical Structure| N/A 同义名 : 重组小鼠MMP-9蛋白(C-10His, HEK293) ;Recombinant Mouse MMP-9 (C-10His, HEK293); Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
CAS号 : N/A
货号 : A2925972
分子式 : -
纯度 : 95% determined by reducing SDS-PAGE.
分子量 : 80.2 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -70°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 may be divided into five distinct domains: a prodomain which is cleaved upon activation, a gelatinbinding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a prolinerich linker region, and a carboxyl terminal hemopexinlike domain.