Mouse MBL-2 (HEK293)
产品说明书
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同义名 : | 重组小鼠MBL-2蛋白(Tag free, HEK293) ;Recombinant Mouse MBL-2 (HEK293); Mannose binding lectin (C); isoform CRA_b; Mannose-binding protein C; Mbl2; MBL-2; Mannose Binding Lectin 2 |
| CAS号 : | N/A | |
| 货号 : | A2925111 | |
| 分子式 : | - | |
| 纯度 : | 90% determined by reducing SDS-PAGE. | |
| 分子量 : | 24 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation. | ||