Mouse CD28 (C-Fc-6His, HEK293)

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Chemical Structure| N/A 同义名 : 重组小鼠CD28蛋白(C-Fc-6His, HEK293) ;Recombinant Mouse CD28 (C-Fc-6His, HEK293); T-cell-specific surface glycoprotein CD28; CD28
CAS号 : N/A
货号 : A2924925
分子式 : -
纯度 : 95% determined by reducing SDS-PAGE.
分子量 : 43 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.