Human SIRPG (C-Fc, HEK293)
产品说明书
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同义名 : | 重组人SIRPG蛋白(C-Fc, HEK293) ;Recombinant Human SIRPG (C-Fc, HEK293); Signal-Regulatory Protein Gamma; SIRP-Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein Beta-2; SIRP-b2; SIRP-Beta-2; CD172g; SIRPG; SIRPB2 |
| CAS号 : | N/A | |
| 货号 : | A2924842 | |
| 分子式 : | - | |
| 纯度 : | 90% determined by reducing SDS-PAGE. | |
| 分子量 : | 63.9 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
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| 描述 | Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. | ||