Human ALK-1 (C-Fc, HEK293)
产品说明书
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同义名 : | 重组人ALK-1蛋白(C-Fc, HEK293) ;Recombinant Human ALK-1 (C-Fc, HEK293); Serine/Threonine-Protein Kinase Receptor R3; SKR3; Activin Receptor-Like Kinase 1; ALK-1; TGF-B Superfamily Receptor Type I; TSR-I; ACVRL1; ACVRLK1; ALK1 |
| CAS号 : | N/A | |
| 货号 : | A2924401 | |
| 分子式 : | - | |
| 纯度 : | 90% determined by reducing SDS-PAGE. | |
| 分子量 : | 37.6 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair. | ||