Human TPSB2 V2 (C-6His, HEK293)
产品说明书
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同义名 : | 重组人TPSB2 V2蛋白(C-6His, HEK293) ;Recombinant Human TPSB2 V2 (C-6His, HEK293); Tryptase Beta-2; Tryptase-2; Tryptase II; TPSB2; TPS2 |
| CAS号 : | N/A | |
| 货号 : | A2924150 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 29.4 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders. | ||