Human TGFBR2 (C-Fc, HEK293)
产品说明书
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同义名 : | 重组人TGFBR2蛋白(C-Fc, HEK293) ;Recombinant Human TGFBR2 (C-Fc, HEK293); TGF-beta receptor type-2; TGF-beta type II receptor; TGFBR2; Transforming growth factor-beta receptor type II |
| CAS号 : | N/A | |
| 货号 : | A2924014 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 42.6 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
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| 描述 | TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors. | ||