Human Serpin E2 (C-6His)
产品说明书
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同义名 : | 重组人Serpin E2蛋白(HEK293, C-6His) ;Recombinant Human Serpin E2 (C-6His) |
| CAS号 : | N/A | |
| 货号 : | A2900853 | |
| 分子式 : | - | |
| 纯度 : | 95% >=95% as determined by reducing SDS-PAGE. | |
| 分子量 : | 0 | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -70°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 描述 | 产品名称：Recombinant Human Serpin E2 (C-6His)理论分子量：42.7 KDa蛋白种属：Human表达系统：Human Cells蛋白表达区间：Ser20-Pro397标签：C-6His剂型：液体纯度：≥95% as determined by reducing SDS-PAGE.储存条件：储存温度≤-70°C，收到后可稳定保存6个月。 储存于≤-70°C，开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装，尽量减少反复冻融次数。产品背景：Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown that Serpin E2 is a novel target of ERK signaling involved in human colorectal tumorigenesis. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction. | ||