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描述 | 产品名称:Recombinant Human CFB (C-6His)理论分子量:84.07 KDa蛋白种属:Human表达系统:Human Cells蛋白表达区间:Thr26-Leu764标签:C-6His剂型:液体纯度:≥95% as determined by reducing SDS-PAGE.储存条件:储存温度≤-70°C,收到后可稳定保存6个月。 储存于≤-70°C,开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装,尽量减少反复冻融次数。产品背景:Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. |