Human CCL2

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Chemical Structure| N/A 同义名 : 重组人CCL2蛋白(E.coli, tag free) ;Recombinant Human CCL2
CAS号 : N/A
货号 : A2900703
分子式 : -
纯度 : 95% >=95% as determined by reducing SDS-PAGE.
分子量 : 0
MDL号 : -
存储条件:

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 产品名称:Recombinant Human CCL2
理论分子量:8.7 KDa
蛋白种属:Human
表达系统:E.coli
蛋白表达区间:Gln24-Thr99
标签:Tag free
剂型:干粉
纯度:≥95% as determined by reducing SDS-PAGE.
储存条件:冻干蛋白应储存在≤-20°C,收到后可稳定保存一年。
溶解后的蛋白溶液可以在2-8°C下保存2-7天。如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
产品背景:The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.