Dihydromethysticin

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Chemical Structure| 19902-91-1 同义名 : (+)-Dihydromethysticin; NSC 112159
CAS号 : 19902-91-1
货号 : A288033
分子式 : C15H16O5
纯度 : 99%+
分子量 : 276.28
MDL号 : MFCD00221731
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(380.04 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Dihydromethysticin is one of the six major kavalactones found in the kava plant and has marked activity on the induction of CYP3A23.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.62mL

0.72mL

0.36mL

18.10mL

3.62mL

1.81mL

36.20mL

7.24mL

3.62mL
参考文献

[1]Ma Y, Sachdeva K, et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos. 2004 Nov;32(11):1317-24.

[2]Walden J, von Wegerer J, et al. Effects of kawain and dihydromethysticin on field potential changes in the hippocampus. Prog Neuropsychopharmacol Biol Psychiatry. 1997 May;21(4):697-706.