Fendiline HCl

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Chemical Structure| 13636-18-5 同义名 : Fendiline盐酸盐 ;Fendiline (hydrochloride); Fendiline hydrochloride
CAS号 : 13636-18-5
货号 : A285022
分子式 : C23H26ClN
纯度 : 98+%
分子量 : 351.91
MDL号 : MFCD00079301
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 30 mg/mL(85.25 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 1.5 mg/mL(4.26 mM)，配合低频超声，并水浴加热至45℃助溶
生物活性
靶点

  • Calcium Channel
描述 Fendiline hydrochloride is a nonselective calcium channel blocker.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.84mL

0.57mL

0.28mL

14.21mL

2.84mL

1.42mL

28.42mL

5.68mL

2.84mL
参考文献

[1]Cunningham JJ, Orr E, et al. Effects of fendiline on cocaine-seeking behavior in the rat. Psychopharmacology (Berl). 2015 Dec;232(24):4401-10.

[2]Jan CR, Lee KC, et al. Fendiline, an anti-anginal drug, increases intracellular Ca2+ in PC3 human prostate cancer cells. Cancer Chemother Pharmacol. 2001 Jul;48(1):37-41.