Desmethylicaritin

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Chemical Structure| 28610-31-3 同义名 : -
CAS号 : 28610-31-3
货号 : A267771
分子式 : C20H18O6
纯度 : 97%
分子量 : 354.35
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 8-Prenylkaempferol, a natural product isolated and purified from the roots of Sophora flavescens, is an effective agent for attenuating pro-inflammatory NO induction, induces differentiation/maturation of MC3T3-E1 osteoblasts by BMP-2/p38/Runx2 pathways, and may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and IRF-3 and in part by interfering with IκB degradation which subsequently decreases NF-κB translocation.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.82mL

0.56mL

0.28mL

14.11mL

2.82mL

1.41mL

28.22mL

5.64mL

2.82mL
参考文献

[1]Chiou WF, Chen CC, Wei BL. 8-Prenylkaempferol Suppresses Influenza A Virus-Induced RANTES Production in A549 Cells via Blocking PI3K-Mediated Transcriptional Activation of NF-κB and IRF3. Evid Based Complement Alternat Med. 2011;2011:920828.

[2]Chiou WF, Lee CH, et al. 8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription. Life Sci. 2011 Feb 14;88(7-8):335-42.