Farrerol
产品说明书
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同义名 : | - |
| CAS号 : | 24211-30-1 | |
| 货号 : | A264602 | |
| 分子式 : | C17H16O5 | |
| 纯度 : | 98% | |
| 分子量 : | 300.31 | |
| MDL号 : | MFCD28347824 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 120 mg/mL(399.59 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Farrerol is a natural product isolated and purified from the leaves of Rhododendron dauricum L. with antioxidative activity. It inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. Farrerol has protective effects against H2O2-induced apoptosis in EA.hy926 cells, and suggests that farrerol is a potential candidate for the intervention of endothelial-injury-associated cardiovascular diseases. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.33mL 0.67mL 0.33mL |
16.65mL 3.33mL 1.66mL |
33.30mL 6.66mL 3.33mL |
| 参考文献 |
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