Methylophiopogonanone A

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Chemical Structure| 74805-92-8 同义名 : -
CAS号 : 74805-92-8
货号 : A261212
分子式 : C19H18O6
纯度 : 99+%
分子量 : 342.34
MDL号 : N/A
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(306.71 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Methylophiopogonanone A, a natural product isolated and purified from the roots of Ophiopogon japonicus with anti-inflammatory and anti-oxidative properties, has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tight junction proteins.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.92mL

0.58mL

0.29mL

14.61mL

2.92mL

1.46mL

29.21mL

5.84mL

2.92mL
参考文献

[1]Lin M, Sun W, et al. Methylophiopogonanone A Protects against Cerebral Ischemia/Reperfusion Injury and Attenuates Blood-Brain Barrier Disruption In Vitro. PLoS One. 2015 Apr 21;10(4):e0124558.