N-Boc-piperazine

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Chemical Structure| 57260-71-6 同义名 : 哌嗪-1-羧酸叔丁酯
CAS号 : 57260-71-6
货号 : A256884
分子式 : C9H18N2O2
纯度 : 98%
分子量 : 186.25
MDL号 : MFCD00075265
存储条件：

Pure form Keep in dark place, inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 N-Boc-piperazine serves as an alkyl/ether-based linker in the creation of PROTAC PD-1/PD-L1 degrader-1, showcasing its utility in the assembly of PROTACs that target and degrade specific proteins using the cell's ubiquitin-proteasome system[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.37mL

1.07mL

0.54mL

26.85mL

5.37mL

2.68mL

53.69mL

10.74mL

5.37mL
参考文献

[1]Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.