Lupalbigenin

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Chemical Structure| 76754-24-0 同义名 : -
CAS号 : 76754-24-0
货号 : A253820
分子式 : C25H26O5
纯度 : 98+%
分子量 : 406.47
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Lupalbigenin, a natural product isolated and purified from the roots of Glycyrrhiza uralensis Fisch, sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins, and shows promising cytotoxic effects toward HL-60 cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.46mL

0.49mL

0.25mL

12.30mL

2.46mL

1.23mL

24.60mL

4.92mL

2.46mL
参考文献

[1]Sangmalee S, Laorpaksa A, et al. Bioassay-Guided Isolation of Two Flavonoids from Derris scandens with Topoisomerase II Poison Activity. Biol Pharm Bull. 2016;39(4):631-5.

[2]Ausawasamrit A, Itthiwarapornkul N, et al. Lupalbigenin from Derris scandens Sensitizes Detachment-induced Cell Death in Human Lung Cancer Cells. Anticancer Res. 2015 May;35(5):2827-34.