Oct3/4-inducer-1

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Chemical Structure| 1016535-83-3 同义名 : MDK35833
CAS号 : 1016535-83-3
货号 : A245242
分子式 : C15H12FNO
纯度 : 99%+
分子量 : 241.26
MDL号 : MFCD09929139
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(435.21 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Oct3/4-inducer-1 (referred to as compound 2) stands out as a potent inducer of Oct3/4, a key pluripotency transcription factor. This compound notably promotes the expression and stabilization of Oct3/4 and amplifies its transcriptional activity across various human somatic cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.14mL

0.83mL

0.41mL

20.72mL

4.14mL

2.07mL

41.45mL

8.29mL

4.14mL
参考文献

[1]Cheng X, et al. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers. J Med Chem. 2015;58(12):4976-4983.