Alkyne-PEG4-maleimide

产品说明书

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Chemical Structure| 1609651-90-2
CAS号 : 1609651-90-2
货号 : A230710
分子式 : C18H26N2O7
纯度 : 97%
分子量 : 382.41
MDL号 : MFCD22380740
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C
参考文献

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

[2]Lyon RP, Setter JR, Bovee TD, Doronina SO, Hunter JH, Anderson ME, Balasubramanian CL, Duniho SM, Leiske CI, Li F, Senter PD. Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates. Nat Biotechnol. 2014 Oct;32(10):1059-62.

[3]Knight P. Hydrolysis of p-NN'-phenylenebismaleimide and its adducts with cysteine. Implications for cross-linking of proteins. Biochem J. 1979 Apr 1;179(1):191-7.