Puerarin
产品说明书
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同义名 : | Kakonein; NPI 031G |
| CAS号 : | 3681-99-0 | |
| 货号 : | A228947 | |
| 分子式 : | C21H20O9 | |
| 纯度 : | 97% | |
| 分子量 : | 416.38 | |
| MDL号 : | MFCD00063399 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(120.08 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Puerarin is the major bioactive ingredient derived from the root of the Pueraria lobata .The neuroprotective effect of puerarin against Aβ‐induced neurotoxicity is related to suppression of apoptosis. Puerarin had a cerebral vasodilatory effect on rat basilar artery rings precontracted with U46619 (100 nm), which brought out 50% inhibition (IC50) of 304 ± 49 µm. Additionally, puerarin (10–160 µm) decreased NO production in rat aortic cells in a concentration‐dependent manner.Puerarin enhanced the mRNA expression of osteoprotegerin and alkaline phosphotase (ALP), whereas it impeded the mRNA expression of receptor activator of NF‐κB ligand in rat osteoblast‐like UMR106 cells[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.40mL 0.48mL 0.24mL |
12.01mL 2.40mL 1.20mL |
24.02mL 4.80mL 2.40mL |
| 参考文献 |
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