Nodosin

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Chemical Structure| 10391-09-0 同义名 : -
CAS号 : 10391-09-0
货号 : A222090
分子式 : C20H26O6
纯度 : 99+%
分子量 : 362.42
MDL号 : MFCD20261062
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(331.11 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Nodosin, a natural product isolated and purified from the herbs of Isodon serra with anti-inflammatory function of Nodosin via inhibition of IL-2, and provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transplantation.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.76mL

0.55mL

0.28mL

13.80mL

2.76mL

1.38mL

27.59mL

5.52mL

2.76mL
参考文献

[1]Wang CF, Wang ZY, et al. Preconditioning donor liver with Nodosin perfusion lessens rat ischemia reperfusion injury via heme oxygenase-1 upregulation. J Gastroenterol Hepatol. 2012 Apr;27(4):832-40.

[2]Li J, Du J, et al. Anti-inflammatory function of Nodosin via inhibition of IL-2. Am J Chin Med. 2010;38(1):127-42.