1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

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Chemical Structure| 3719-45-7 同义名 : Nudifloric Acid
CAS号 : 3719-45-7
货号 : A215227
分子式 : C7H7NO3
纯度 : 97%
分子量 : 153.14
MDL号 : MFCD00031002
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(685.65 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.53mL

1.31mL

0.65mL

32.65mL

6.53mL

3.26mL

65.30mL

13.06mL

6.53mL
参考文献

[1]Suh W, et al. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul). 2017 Mar 1;25(2):165-170.

[2]Suh W, Nam G, Yang WS, Sung GH, Shim SH, Cho JY. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul). 2017 Mar 1;25(2):165-170