Methylmalonic acid

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Chemical Structure| 516-05-2 同义名 : Methylpropanedioic acid; Methylmalonate; NSC 25201; MMA; Isosuccinic Acid
CAS号 : 516-05-2
货号 : A211160
分子式 : C4H6O4
纯度 : 97%
分子量 : 118.09
MDL号 : MFCD00002656
存储条件:

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(889.17 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 100 mg/mL(846.83 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 Vitamin B-12 is required for the conversion of methylmalonic acid (MMA) to succinyl-CoA and homocysteine (HC) to methionine. Therefore, it is clear that methylmalonic acid is more specific for vitamin B-12 deficiency than HC [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

8.47mL

1.69mL

0.85mL

42.34mL

8.47mL

4.23mL

84.68mL

16.94mL

8.47mL

参考文献

[1]Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843.