K-7174

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Chemical Structure| 191089-59-5 同义名 : -
CAS号 : 191089-59-5
货号 : A209985
分子式 : C33H48N2O6
纯度 : 98%
分子量 : 568.74
MDL号 : MFCD12922512
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 K-7174 is a cell adhesion inhibitor and inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.76mL

0.35mL

0.18mL

8.79mL

1.76mL

0.88mL

17.58mL

3.52mL

1.76mL
参考文献

[1]Imagawa S, Nakano Y, et al. A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA. FASEB J. 2003 Sep;17(12):1742-4. Epub 2003 Jul 18.

[2]Umetani M, Nakao H, et al. A novel cell adhesion inhibitor, K-7174, reduces the endothelial VCAM-1 induction by inflammatory cytokines, acting through the regulation of GATA. Biochem Biophys Res Commun. 2000 Jun 7;272(2):370-4.